I loosely adapted Paper Mario: The Thousand Year Door into 5e. Very loosely; I didn’t take any of the places or people, but I did the overarching “go find these lost relics so we can stop the world from ending” thing. I think it went well.

My advice would be that the only canon that matters is the one that you build with your players at the table. Use your inspiring source material as the starting point, not the sum total of your game.