The word akathisia comes from the Greek words meaning “not sitting.” The name is fitting because people experiencing akathisia feel an intense inner urge to move and are unable to remain still.

Patients often pace, rock back and forth, shift their weight repeatedly, or constantly move their legs. Many describe the sensation as unbearable.

Beyond physical restlessness, akathisia can trigger severe anxiety, irritability, agitation, and, in some cases, aggressive behavior.

Among antipsychotic medications, Haloperidol is one of the drugs most commonly associated with akathisia. Studies suggest that even a single dose can trigger akathisia. [1] Fortunately, akathisia typically resolves once the medication is discontinued.