• i_have_no_enemies@lemmy.worldOP
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    1 year ago

    my dad is refusing to take vaccines because he thinks taking it will automatically make him vote dem because of nano-machine in them.

    he also thinks vaccines are kind of HRT.

    anyways how’s your day?

    • Pons_Aelius@kbin.social
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      1 year ago

      I hope you are an adult and no longer live with your parents.

      If that is the case remember this. If you cannot have pleasant encounters with him, you are under no obligation to have them at all.

      • Kecessa@sh.itjust.works
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        1 year ago

        No obligation to keep seeing them, would be kind of hard not to have parents 😛

            • Pons_Aelius@kbin.social
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              1 year ago

              You sound like you have a good relationship with your parents, many don’t.

              You can be there for them when they need you without putting up with the anti-vax ravings you mentioned. It is called setting boundaries.

              You do what you think is right but also understand that is not a universal thing for all people.

              • i_have_no_enemies@lemmy.worldOP
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                1 year ago

                You sound like you have a good relationship with your parents

                not really.

                i think it is best to minimize contact but not keep null, since these kind of people are self destructive.

                that’s the only reason i stayed , for their health issues.

                • mild_deviation@programming.dev
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                  1 year ago

                  What about your health? Your mental health in particular.

                  Your parents raising you is not something you owe them for. You didn’t choose to exist; they chose that for you. Raising you is the bare minimum they can do after making a choice like that. And now that you are older, you can reflect on the manner in which you were raised and decide what your relationship with them needs to look like so you can keep your sanity.

            • mrbaby@lemmy.world
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              1 year ago

              I’ve noticed my parents have reverted to basically defiant teenagers.

              My mom can’t keep a basic job and lives in a camper. I’ve been sending her $1k+ a month to keep her fed and off the streets. My dad left and disappeared for 3 years while he ran around doing weird shit. He’s kept a steady job but found another younger family. Now he’s just a distance acquaintance. When i left home 10+ years ago they had a 3000sqft ranch house, pretty well put together, retired after 20yrs in the USAF. That house turned into an episode of hoarders, particularly with animals. Piss and shit everywhere, floors were torn down to the plywood, walls soaked in piss, that weird “smoker dust” hanging off the popcorn ceiling, unknown number of feral cats took over the basement. She lived there without paying the mortgage for years and years and finally got evicted a couple years ago… I would fucking kill to have a $1300 mortgage on a 3k sqft 1acre property. My rent for 900sqft is almost double. It’s sickening she let it go like that. This all happened around 2015… hmm

              It really sucks knowing that if shit hits the fan for any of us (their kids) we have zero safety net to fall back on.

            • Rbnsft@lemm.ee
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              1 year ago

              Nope they chose to get a child. You dont have to Do anything for them.

        • Mac@mander.xyz
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          11 months ago

          The “them” in that sentence refers to “encounters” not “parents”.

      • PhobosAnomaly@feddit.uk
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        1 year ago

        It’s all that government big pharma stuff that have given me moobs, things like:

        • Covid-19 vaccines;
        • Fluoride in toothpaste and tapwater;
        • Chemtrails;
        • a horrendous diet and little exercise;
        • pride flags
        • SuckMyWang@lemmy.world
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          11 months ago

          I’ll show my man boobs to anyone who wants to see them. Usually people tell me to stop showing them and say things like “gross” and call me bear tits but that hasn’t stopped me from whipping them out on every occasion and non occasion

    • Kaavi@lemmy.world
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      1 year ago

      I watched birds are not real Ted talk the other day, I think it was awesome to give a perspective on the conspiracy stuff and how people run with it.

      If it flies, it spies. 🐣

    • Dark Arc@social.packetloss.gg
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      1 year ago

      If you have some disposable cash and you’re running into the “watch this video about antivax stuff”. I recently discovered Kagi’s summarizer works on as many YouTube videos as you want (seemingly by processing the audio itself).

      It’s been a bit since I’ve received a video like that, but I think it’ll be a huge time saver for the next one… Or the next similar one…

  • deranger@sh.itjust.works
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    1 year ago

    While I’m sure there is a crazy markup, it’s important to note the cost to produce - as in manufacture - does not include the cost of drug discovery, which is extremely expensive and involves a good amount of risk over a long period of time.

    You can’t just compare the cost of discovering a new drug vs. cost of producing a generic without any research like that.

    • be_excellent_to_each_other@kbin.social
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      1 year ago

      https://jacobin.com/2023/09/big-pharma-research-and-development-new-drugs-buybacks-biden-medicare-negotiation

      Last year, the three largest US-listed pharmaceutical companies by revenues, Pfizer, Johnson & Johnson, and Merck, spent a combined $39.6 billion on R&D. That is, admittedly, a lot of money. But less than Medicare is currently paying on just ten drugs

      While Big Pharma holds vast portfolios of existing patents for prescription drugs, the innovation pipeline for new drugs actually has very little to do with Big Pharma. In reality, public sources — especially the NIH — fund the basic research that makes scientific breakthroughs. Then small, boutique biotech and pharmaceutical firms take that publicly generated knowledge and do the final stages of research, like running clinical trials, that get the drugs to market. The share of small companies in the supply of new drugs is huge, and it’s still growing. Fully two-thirds of new drugs now come from these small companies, up from one-third twenty years ago. It is not the research labs of Pfizer that are developing new drugs.

      • Rinox@feddit.it
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        1 year ago

        Pfizer COVID vaccine wasn’t researched or developed by them. It was developed by the German BioNTech.

        Still, bringing it to market at the required volumes requires extreme amounts of capital, there’s a reason no one can enter the club.

      • repungnant_canary@lemmy.world
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        1 year ago

        I like Lemmy for exactly this - whenever someone incorrect makes a statement they’re factchecked.

        Thank you kind person for finding and sharing that source.

        • flawedFraction@lemmy.world
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          OP didn’t make an incorrect statement though. What they stated was an important part of the equation. I think a lot of people don’t take that type of thing into account and they will read what this post says and assume that Pfizer should be charging $13, or maybe something pretty close like 15 or 20. Clearly 1400 is far far too high, 13 is too low. A reasonable price allows the manufacturer to be successful while not gouging consumers lies somewhere in between, but much much closer to the low end than the high. To me that’s really what the person you are responding to is giving evidence for.

    • Nate Cox@programming.dev
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      1 year ago

      R&D on drugs is insanely expensive, but the protections put in place with the pricing are also a bit absurd. Most drug companies will lock down the formula for a period of time and price the drug aggressively for a short time (like a few years) and then open the formula up to generics who buy it and sell the same damn thing for a fraction of the cost.

      For clarity I’m agreeing with you that the price is largely due to non-manufacturing costs and the article is misleading as a result, but I also wanted to say that the whole industry is a testament to capital over humanity.

    • clausetrophobic@sh.itjust.works
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      1 year ago

      Fuck off with the big pharma apologetics.

      Boo hoo the corporation got millions in taxpayer money to develop a vaccine and now they have to profit off of it. I feel so bad for them.

      This is subtle astroturfing.

      • just another dev@lemmy.my-box.dev
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        1 year ago

        By that same logic: it costs a couple of cents to burn a dvd or to transfer a few gigabytes, yet games costs $60.

        All the commenter above you is saying is don’t mix up the cost to develop with the cost to mass produce,

        • 𝒍𝒆𝒎𝒂𝒏𝒏@lemmy.one
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          1 year ago

          I’m going to be unreasonable because I don’t like the ethics behind Pharma companies.

          They should eat the loss; their research was healthily subsidised by the taxpayer

          • FMT99@lemmy.world
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            1 year ago

            I’m personally of the opinion that all medical research should be tax funded. But given our current situation, if you tell these companies to ‘eat the loss’ they will simply stop producing new medicines.

            • pinkdrunkenelephants@lemmy.cafe
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              1 year ago

              Oh stop. The government should be running the pharaceutical industry then, not private companies.

              Stop simping for evil corporations that don’t give a shit about you.

              • FMT99@lemmy.world
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                Reading comprehension is tough I know. I indeed believe essential services including medical research should be government run.

                But since that is not the case right now you can’t expect companies to operate on a non profit basis. If stating obvious facts is simping then I guess you can call me a simp.

            • gordon@lemmy.world
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              1 year ago

              Oh no, whatever will we do if old dudes can’t have 6 different types of boner pills?

              • Same@lemmy.world
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                1 year ago

                Pharma companies spend a majority of their time trying to make new unique drugs, they just fail most of the time. The ones that succeed tend to be ones that are similar to ones that succeeded in the last, which is why you get multiple drugs in the same class, but it’s not all they do. For example, we’ve essentially cured some types of cystic fibrosis, and there’s an effective vaccine for malaria now - all developed in the last 10 years.

                I don’t want to pretend that the big pharma companies aren’t evil, but they do have incentives that align with improving human health.

              • FMT99@lemmy.world
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                1 year ago

                It’s real easy to sit on the sidelines and spew hate. Not much of a life though.

        • be_excellent_to_each_other@kbin.social
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          1 year ago

          All the commenter above you is saying is don’t mix up the cost to develop with the cost to mass produce,

          That cost to develop was likely not borne by Pfizer in the first place.

          https://jacobin.com/2023/09/big-pharma-research-and-development-new-drugs-buybacks-biden-medicare-negotiation

          Last year, the three largest US-listed pharmaceutical companies by revenues, Pfizer, Johnson & Johnson, and Merck, spent a combined $39.6 billion on R&D. That is, admittedly, a lot of money. But less than Medicare is currently paying on just ten drugs

          While Big Pharma holds vast portfolios of existing patents for prescription drugs, the innovation pipeline for new drugs actually has very little to do with Big Pharma. In reality, public sources — especially the NIH — fund the basic research that makes scientific breakthroughs. Then small, boutique biotech and pharmaceutical firms take that publicly generated knowledge and do the final stages of research, like running clinical trials, that get the drugs to market. The share of small companies in the supply of new drugs is huge, and it’s still growing. Fully two-thirds of new drugs now come from these small companies, up from one-third twenty years ago. It is not the research labs of Pfizer that are developing new drugs.

        • Saxoboneless@lemmy.world
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          1 year ago

          …and the video game industry makes more money than any other entertainment industry. Yes, these things should cost more than just their production cost, but there is currently an obscene amount of money being made by the people at the top of these industries - y’know, the ones whose main role in making and distributing the product is just already being obscenely wealthy. And while I don’t really care if AAA games are overpriced if they’re only $60, I do care if life-saving meds are being held for ransom.

          Do y’all need reminded that insulin, a life-or-death drug that’s been around since the fucking 1920s, only costs at most $10 to make but currently retails for up to $300 a vial? It does not fucking matter whether or not this particular treatment should cost $13 or $90, the markup on any life saving drug being over 1,000% is blatant price gauging at the expense of human life, and the fact that the pharmaceutical industry does this all the time is common fucking knowledge. Anything approaching a defense of this shit either is in fact astroturfing or is so braindead as to call it a necessity that a publicly traded company demand the sick either choose debt or the grave.

      • LufyCZ@lemmy.world
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        1 year ago

        Are we talking about the vaccine here? Sounds like a post-exposure drug to me

      • RBG@discuss.tchncs.de
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        1 year ago

        Guess this comment of mine will also get deleted but here goes nothing.

        The article is about antiviral medicine, not a vaccine. So you are getting angry at the wrong thing.

    • Sprokes@lemmy.ml
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      That’s just an excuse because many drugs are sold at prices much lower what they are sold in the US. They are not selling them at loss in other countries.

      • LufyCZ@lemmy.world
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        Definitely not at a loss to produce no, but maybe a loss overall.

        My bet is that the US subsidizes R&D by paying obscene amounts for the drugs and the EU and others just serve as extra income

        • Sprokes@lemmy.ml
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          That’s what they make you believe. Why American still pay high prices for insulin? It doesn’t cost that much to produce. It just those companies are paying politicians to keep things in their advantages and give you those excuses.

      • RBG@discuss.tchncs.de
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        Well here you go again when people with no scientific education pull up literature as a gotcha. Thanks for giving me flashbacks to the high times of the pandemic. Sorry for the harsh reply but its posts like this that just funnel into misinformation around this already heavily polarized topic.

        To explain, Paxlovid is not a vaccine, it is an actual medicine/treatment. So it was not funded by taxpayers as the article states. Unless there is some other info on how this specific medicine was also funded by taxpayers of course, I am not an expert on research funding. But the article only mentions vaccine research.

        That said, I also do not think its a fair price necessarily. But it is true one should not equate production price as a fair price as R&D of drugs have high costs, mostly also because a lot of drug programs fail, making all prior investment to them a loss.

    • SuckMyWang@lemmy.world
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      Yes we can. It’s just doesn’t give a good faith assessment of the situation. And why would I want to do that if it’s counter to my rigid world view? sigh better add an /s

      • Rinox@feddit.it
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        I don’t think he meant to the consumer. EU countries can negotiate for the price with pharmaceutical companies, so they can lower the price.

        In the US insurance companies can try to negotiate, but their weight is quite low, and the federal government (medicaid, medicare) is forbidden by law to negotiate. Whichever price pharma sets, it’s that.

        • Kaavi@lemmy.world
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          1 year ago

          Sounds crazy they are but allowed to negotiate?

          Is that the same for anything else the government buys? I can’t imagine the army buying 100 tanks and just paying the first price they get?

            • 𝒍𝒆𝒎𝒂𝒏𝒏@lemmy.one
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              1 year ago

              In fact it’s the first time the government will be able to negotiate with pharmaceutical companies!

              Yes! That’s a great start 👌 especially if the negotiator is NOT getting a kickback from Pharma for negotiating a high price

          • TeamAssimilation@infosec.pub
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            1 year ago

            It’s like

            – Arms dealer: Each tank cost me 500,000 dollars to make. Give me 5 billion for each.

            – Let’s negotiate. How about 500 million instead?

            – Arms dealer: Fiiine, but only because you’re a good client.

            • dirtbiker509@lemm.ee
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              11 months ago

              This is legitimately how it works in the US between insurance and pharma/medical.

              I just had a baby and I added up the total bill from the hospital and it was $100,000. We were in the hospital for 3 days. My insurance “negotiated” it down to $26,000, and I paid $3000.

              The $100,000 is completely made up from the beginning. Pharma and medical just slap big ass ridiculous numbers down, then the insurance fake negotiates down to a still completely ridiculous number, then that cost has to get eaten by people who pay into insurance, which is basically everyone.

        • kambusha@feddit.ch
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          1 year ago

          … forbidden by law to negotiate.

          Is that true? Is there a legitimate reason why they shouldn’t be able to?

          • TeamAssimilation@infosec.pub
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            1 year ago

            Because medicine shouldn’t become a flea market where you’re gambling your health against profit maximization.

            Give pharmaceutical companies a fair price scale where they can profit, don’t let them hyperinflate prices without justification.

            It’s not the same if Apple prices their phones at 20,000 USD and you decide you’re buying other brand, pharma plays these extortion games after they have captured enough market/regulation so most people have to pay or stay sick.

  • RVMWSN@lemmy.ml
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    1 year ago

    Intellectual property is a scam. A commonly heard defense of intellectual property is that it is needed for companies to fund their R&D. However pharmaceutical companies typically spent a lot more money on marketing & sales than they do on R&D. Big Pharma spending money on marketing and sales is harmful to our health. Apparently it’s a lot more lucrative to get people drugged up on painkillers or whatever than to discover new medicine. If we didn’t have intellectual property then we would have competition resulting in the lowest possible medicine prices. Companies would have no money for R&D but the government could fund R&D through universities. We shouldn’t blame the players, we created a system that produces these bad actors. Let’s change the system.

      • piecat@lemmy.world
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        There is some level of R&D they do to productize it, manufacturability and scaling. And running drug safety trials cannot be cheap, especially the liability insurance.

        That all said, I think it’s criminal that the university labs pay so little. PhD students barely make over $40k, set by the NIH. Not adjusted for CoL either.

        I think I have more of an issue with the for-profit nature of pharma companies. Shareholders shouldn’t be involved in medicine.

      • artic@lemmy.blahaj.zone
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        1 year ago

        I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations I hate corporations i hate corporations i hate corporations

      • Pyr_Pressure@lemmy.ca
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        1 year ago

        The woman who got the nobel prize for the mRNA research that led to the Pfizer vaccine did a lot of it while employed at Pennsylvania University before they fired her because they didn’t see the research leading to making them money. Then she moved on to Biontech where she continued the research.

        I’m not sure how much was done at the university but it was probably not insignificant and then biontech got lucky and snapped it up for basically free.

      • frezik@midwest.social
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        11 months ago

        I’m always curious about the actual numbers. Here’s their R&D budget by year:

        https://www.statista.com/statistics/267810/expenditure-on-research-and-development-at-pfizer-since-2006/

        And their overall revenue:

        https://www.pfizer.com/sites/default/files/investors/financial_reports/annual_reports/2022/performance/

        In 2020, their revenue was about $40B on $8.5B in R&D cost. They had a huge revenue increase the last few years, with 2022 being $100B, but R&D only increased to about $11B.

        So they do have R&D, but it’s not that big compared to the money they’re bringing in. Their net income has increased substantially, as well.

          • IDontHavePantsOn@lemm.ee
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            11 months ago

            In the bio industries R&D has almost exclusively become just the D. We like to think that there are a bunch of scientists doing lifelong, painstaking research to develop new drugs or treatments within the labs at Pfizer, Merk, Lilly, or whatever, but a significant portion of the research is done at small independent or school funded labs.

            Once one of those small labs creates a decent treatment that will likely pass government testing, a large corp will buy it and say “We just made this brand new thing!”. Really though, their R&D budget is spent on acquisition, production, supply chain development, and marketing.

            • Average_Squid@sh.itjust.works
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              11 months ago

              Working in R&D in a few different positions in my career and this is absolutely the case. Hell some of them you could equate to white label SaaS products. Using research from universities putting it in a neat package and selling it.

              • IDontHavePantsOn@lemm.ee
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                11 months ago

                The corporate bio industry is so fucked up I can’t even begin to describe it. I tell my friends and family stories, but I sound like an insane person to them. The scale at which money is thrown around is just too large for most people to imagine.

                Like this: imagine a worker that makes less than $35k per year processes, and is soley responsible for $20M in products, per month. Product that people all around the world not only use, but ingest. Now imagine that that one worker is the only one in the world who knows how that product is processed. That’s how bio manufacturers work.

        • AEsheron@lemmy.world
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          11 months ago

          In addition to that, I’ve heard that a large portion of that R&D spending is on iterating drugs they already own so that when the patent runs out they can patent a new version and lobby the old one to be made obsolete so generics can’t be made.

    • uis@lemmy.world
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      AFAIK some US agency did R&D for COVID, they just bribed sponsored Right People

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    11 months ago

    From the bottom of my heart, fuck you Pfizer. I have had Covid twice, had my blood oxygen drop as low as 79, and I would still rather die a miserable covid death than suffer the injustice of being greed raped by the absolute worst caricature of capitalist pigs that actually came to life. I hope that money makes your board members miserable and can’t do much to treat the uncurable, flesh eating disease your evil pig carcasses should be justifiably riddled with by karma, leaving your kids to donate your disgustingly afforded estate to charity to cleanse themselves of the nasty aftertaste of human suffering, the faint stink of people who are trying to take paxlovid and recover from a major virus in the rain and vulnerable cold because they can’t afford both rent and medicine, after your death. Burn in hell, you uncaring scum.

    EDIT: I realize this is a lot of vitrol to throw out into the universe, but they likely won’t ever see this on Lemmy, and to make matters worse they clearly won’t care anyway. It’s just my own version of catharsis, I guess

    • eskimofry@lemmy.world
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      1 year ago

      Much better strategy: you take the medicine… survive… and refuse to pay in protest. Sure, you might get sued for non-payment of bills… then a bunch of people can fight a class action lawsuit against pfizer.

    • vacuumflower@lemmy.sdf.org
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      had my blood oxygen drop as low as 79

      Oh, my aunt’s husband was in this situation. And they live in Armenia, where normal Covid treatment was, is and will be virtually nonexistent.

      He’s thankfully alive and didn’t lose any of his wits.

    • PilferJynx@lemmy.world
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      I get the anger. We really need to fully socialize these medical development centers. But on the other hand, they did most of the work. They didn’t have to.

      • Raiderkev@lemmy.world
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        I’m sure the research was publicly funded, and the profit will be private as is tradition.

      • I_Fart_Glitter@lemmy.world
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        11 months ago

        Yep, that Pfizer for you, using taxpayer money to R&D drugs they will use to price gouge the public who paid for it, out of the kindness of their hearts.

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    Didn’t the government fund the development? So… it’s not like they need so much to recover R&D right?

    • Isakk86@lemmy.world
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      Welcome to the United States. Everything is subsidized, then turned around to fuck the average person.

    • Kongar@lemmy.dbzer0.com
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      I know they funded moderna - they basically built Moderna’s new plants including their cmo’s plant so that they could produce at scale. Govt built and funded the plants at risk - prior to fda approval - so that it massively sped up the process to getting the drug in people’s hands. Those plants are now used for other drugs.

      I think - but not 100% sure - Pfizer did it on their own.

      Still - 10,000% is shameful.

    • BrianTheeBiscuiteer@lemmy.world
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      I’m fine with the public-private partnership but money like this needs to come with strings attached. We should’ve made an agreement to cap the price. We developed these drugs under the Trump administration so I really don’t think the impact to poor and middle class citizens has ever been a thought in his mind.

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    Paxlovid kept me alive when I had COVID. This makes me really upset. People will actually die without this.

    • givesomefucks@lemmy.world
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      1 year ago

      I’ll never understand why so many people think middlemen somehow makes shit cheaper…

      Taxes > government research > cheap meds

      With the bonus point of no more pharmaceutical companies selling shit like oxy for profit

      • VinnieFarsheds@lemmy.world
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        1 year ago

        Because they think government is inefficient by default, and a commercial business is motivated towards max efficiency to cut costs. Maybe all of this is true, but in capitalism companies also sell for the optimal price based on price elasticity. No competitors + essential live saving product = high prices.

        • vacuumflower@lemmy.sdf.org
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          Actually in human societies, not just in capitalism.

          People talk about capitalism being bad as if only there people try to eat each other to become richer.

          If you read something about reasons the USSR wouldn’t have more efficient centralized planning, while having necessary machinery and resources, or why it wouldn’t have standardized something, while having the standardization apparatus and planned economy, or why all the Internet-like projects went nowhere in USSR while being much more ambitious due to, again, planned economy, or why despite less fragmentation scale wouldn’t make things cheaper to produce in USSR, but the opposite, and so on - that’s because every reform would mean someone losing influence, and that someone would naturally use that influence to resist reform.

          It’s actually fascinating to read how some of those people really believed in Marxism and Communism, and were even very competent sometimes, but the general architecture made the whole thing less than just a sum of its parts. Really sad, though.

          • Maggoty@lemmy.world
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            11 months ago

            I agree that the problems aren’t just in Capitalism. However, the country with the unofficial historical tagline, “and then it got worse”, may not be the best example. I think China is a really good example of influence peddling outside a free market.

            • vacuumflower@lemmy.sdf.org
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              11 months ago

              Well, China, when its ruling organization still had some consistent ideology, was a copy of Stalin’s USSR, bigger and weaker, give or take. Only it started later.

              Its way off that track started with reforms like Kosygin’s reforms, would those not be neutered.

              I’d say the reason in China this happened was exactly that it was bigger and weaker. It didn’t quite have anything like Soviet industrial establishment, and it had the issues of poverty, hunger etc.

      • vacuumflower@lemmy.sdf.org
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        Because “government research” doesn’t cover mass production and all of the supply chain management. Which is where anything bureaucratic really sucks.

        (Unless you need to build things badly, but fast and on large scale, mobilization-style - see Khruschev-era mass construction in ex-USSR, or, for exotic stuff, older state-built housing in Israel which isn’t that much better).

        Actual production rots very quickly, if centralized and bureaucratic.

        I agree that research requires long-term investment and is in general a completely different thing.

        • givesomefucks@lemmy.world
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          There’s just so much wrong in your comment I can’t address it all…

          But where has anyone said the government had to manufacture it too?

          We’re talking about patents right now.

          The rest of what you said is still wrong, can’t stress that enough, it just also has absolutely nothing to do with what people were talking about…

          • vacuumflower@lemmy.sdf.org
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            There’s just so much wrong in your comment I can’t address it all…

            If you can’t then you’d better say nothing.

            But where has anyone said the government had to manufacture it too?

            You said when talking about pharma companies as middlemen. You remove those middlemen - you have to do tasks they perform.

            We’re talking about patents right now.

            Yes, patent law should be abolished. That’s what I’m talking about while commenting in most threads blaming “capitalism”, because in like 2/3 cases patent law is to blame and not that.

            The rest of what you said is still wrong, can’t stress that enough, it just also has absolutely nothing to do with what people were talking about…

            Thank you for your unsubstantiated opinion which I can beat with that of my own every time, so not sure why you’d even express it without details.

            • givesomefucks@lemmy.world
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              11 months ago

              If you can’t then you’d better say nothing.

              You’ve got a point, I should have said “won’t put the effort in”.

              I looked at your profile, you wait till posts are really old, then spam a bunch of nonsensical replies in it.

              I’m just gonna block you. Everyone wins.

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                11 months ago

                I’m just gonna block you. Everyone wins.

                Not the worst way to look at this, if you want my opinion.

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      People vote for it every two years and are shocked, just shocked when they get precisely what they voted for.

      • eskimofry@lemmy.world
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        1 year ago

        Do you think pfizer and other companies who spend hundreds of millions lobbying would be like “aww shucks! the public voted to curb our shitty behavior, let’s go home!”?

    • vacuumflower@lemmy.sdf.org
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      Ah, trademark laws and patents are obviously governmental stuff. So - not present in some imagined absolute capitalism. And with those abolished (except for stealing authorship still being illegal), I suppose market mechanisms would do their job sufficiently well for this particular case.

      Believing in capitalism is believing in humans making rational and moral choices, anyone to do that would be nuts. That’s a proactive answer to politically active people getting triggered by my comment and labeling me as a member of the other crowd.

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      You have to consider all the R&D they put into it.

      (Didn’t the government pay for most of that?)

      • hydrospanner@lemmy.world
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        11 months ago

        Right?

        In a just world, “the people” would see this pricing, realize that they were the ones who paid for the development of it, and simply seize the company.

        Whether that took the form of government litigation to force the company to offer this at a reasonable price, or simply a mob of people forcing the company’s hand or else they burn it to the ground, either way, there needs to be a stick of fear to go along with the carrot of profit.

        I’m not saying they should make no profit, but this is ridiculous.

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    Seriously, people are acting like this is new. There is no sense in shaming them we’ve had it brought to the mainstream by people like Martin Skhreli and nothing has been done. Martin Skhreli himself is only in jail because of his ponzi schemes, a.k.a. screwing other rich people out of their money. The only reason Pfizer was praised was because it was needed in a time of need and because they hired plenty of lobbyists.

    • postmateDumbass@lemmy.world
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      Ive accepted this behavior as typical and standard issue human nature.

      That is why i am mot having kids, seeing that extinction is the best future for humans. Evolution puts any other intelligence in the universe at risk.

  • Alien Nathan Edward@lemm.ee
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    It’s been too long since the aristocrats were reminded that they need us more than we need them and that they can’t hire enough of us to stop the rest of us once we take an idea to mind.

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    So many Martin Shkrelis out there pricing drugs to the highest level they can get away with. Every big pharmaceutical company does this kind of thing, especially with new drugs.

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    Don’t ever think for a second that pharmaceutical companies did anything during Covid for our benefit. They were working their actuarial tables to figure out how they maximize their profits in the future against sick people dying.

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      They did save millions of lives, though, and allowed us to stop the constant quarantines months or even years early, whatever their motivations (and I’m not as cynical about that as you).

      Meanwhile, all the Internet smartasses who love to criticize the drug industry non-stop did exactly jack shit.

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        There’s nothing wrong with the drugs these companies are developing.

        But stopping production or halting research in curing diseases, just because it isn’t as “profitable” as selling drugs to treat the symptoms rather than the disease. That’s insane.

        Selling drugs at insane markups, when it’s very clear they cost far less in the EU, and they still earn ton of money. That’s insane.

        Patent medicin to keep it out of the hands of sick people, because your other not-as-good drug sells better. That’s insane.

  • db2@sopuli.xyz
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    And who is in charge of making sure this kind of immoral illegal thing doesn’t happen? People who are still somehow allowed to collect kickbacks in exchange for looking the other way.

    • Dave@lemmy.nz
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      We don’t have the information needed to decide whether to be angry.

      Drug studies are costly. We need to know how much R&D cost for this drug, what the average is, what percentage of research never hits the market, and then how many doses of this are expected to be sold over say a 5 year period.

      Then we can work out a rough true cost of each dose. Then we will know whether to be angry.

        • Dave@lemmy.nz
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          Yes, for vaccine research. I don’t know if this specifically was covered. Another thing on the list of things we need to know before we get angry.

        • yiliu@informis.land
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          Much of the research happened long before COVID–at a loss. There’s a reason this miraculous new mDNA vaccine technology appeared out of nowhere just in time for the pandemic: researchers had been working on it for years already, using investments and borrowed money. Government grants just went to finishing the vaccine and scaling up so quickly it was kinda mindboggling. They didn’t just get to stuff the cash in their pockets.

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        I think we’d be better off is we shifted R&D to academia. Sure there’s a fuck ton of bureaucracy in universities, but maybe then our tax dollars will be put to good use, and people learn.

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        https://jacobin.com/2023/09/big-pharma-research-and-development-new-drugs-buybacks-biden-medicare-negotiation

        Last year, the three largest US-listed pharmaceutical companies by revenues, Pfizer, Johnson & Johnson, and Merck, spent a combined $39.6 billion on R&D. That is, admittedly, a lot of money. But less than Medicare is currently paying on just ten drugs

        While Big Pharma holds vast portfolios of existing patents for prescription drugs, the innovation pipeline for new drugs actually has very little to do with Big Pharma. In reality, public sources — especially the NIH — fund the basic research that makes scientific breakthroughs. Then small, boutique biotech and pharmaceutical firms take that publicly generated knowledge and do the final stages of research, like running clinical trials, that get the drugs to market. The share of small companies in the supply of new drugs is huge, and it’s still growing. Fully two-thirds of new drugs now come from these small companies, up from one-third twenty years ago. It is not the research labs of Pfizer that are developing new drugs.

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        Even if R&D cost $100m for this, they’d still only need to sell roughly 80000 doses to make their money back.

        • Dave@lemmy.nz
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          I think you’re grossly underestimating how much things cost.

          • christophski@feddit.uk
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            Haha, you got in there before I corrected my typo. The point still stands though! There’s a whole lot of people in the world, 80k doses is fuck all.

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              Average drug research costs are estimated at between 1-3 billion USD. That’s the average, so some are much more.

              And I’d like to know if this stated price is the sticker price. Insurance companies negotiate much less than sticker price, I live in a country with a government drug department that negotiates much lower prices by doing a single contract for the whole country.

              Is this that stupid thing where the sticker price is high but no one actually pays that, it’s just to make insurance companies feel like they are negotiating good deals?

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        Orrr, hear me out, we can be angry right now without any prep, put in a comment about big corpo greed, and move on the to next Lemmy post.